PBM Module 4b Risk-of-bias-tabel
Risk of bias table for intervention studies (randomized controlled trials; based on Cochrane risk of bias tool and suggestions by the CLARITY Group at McMaster University)
|
Study reference (first author, publication year) |
Was the allocation sequence adequately generated? Definitely yes |
Was the allocation adequately concealed? Definitely yes |
Blinding: Was knowledge of the allocated interventions adequately prevented? Were patients blinded? Definitely yes |
Was loss to follow-up (missing outcome data) infrequent? Definitely yes |
Are reports of the study free of selective outcome reporting? Definitely yes |
Was the study apparently free of other problems that could put it at a risk of bias? Definitely yes |
Overall risk of bias If applicable/necessary, per outcome measure LOW |
|---|---|---|---|---|---|---|---|
|
MacIntyre, 2011 |
Yes Reason: Computer randomization at hospital level |
No information Reason: no information provided |
Definitely no Reason: Healthcare workers were not blinded, no information on outcome assessors |
No information Reason: no information was provided on loss to follow up (no loss to follow up was reported) |
Probably yes Reason: relevant outcomes were reported |
Definitely no Reason: There was a significant difference between the fit tested and non-fit tested group in influenza vaccination status |
HIGH (infection) Reason: high concerns regarding blinding and influenza vaccination status difference between groups |